Forthcoming and Online First Articles

International Journal of Nanoparticles

International Journal of Nanoparticles (IJNP)

Forthcoming articles have been peer-reviewed and accepted for publication but are pending final changes, are not yet published and may not appear here in their final order of publication until they are assigned to issues. Therefore, the content conforms to our standards but the presentation (e.g. typesetting and proof-reading) is not necessarily up to the Inderscience standard. Additionally, titles, authors, abstracts and keywords may change before publication. Articles will not be published until the final proofs are validated by their authors.

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International Journal of Nanoparticles (1 paper in press)

Regular Issues

  • Synergistic antibacterial effect against S. Aureus in combination with Amoxicillin using fluconazole nanoparticles studied under Atomic Force Microscopy.   Order a copy of this article
    by Dania Ahmed, Samina Perveen, Raza Shah, Farid Ahmed 
    Abstract: COVID-19 patients are increasing day by day. The risk of bacteria-virus co-infection also escalates. Because of the extensive use of antibacterial drugs, the drug resistant bacterial strains are increasing. rnAntibiotic resistance caused by pathogenic bacteria has become a major health challenge these days. The key objective was to examine the antibacterial effects of Fluconazole coated silver nanoparticles (Ful-AgNPs) in combination with amoxicillin against bacteria that show resistance to amoxicillin. Here we are reporting a quick, tranquil, and feasible synthetic procedure for the preparation of Ful-AgNPs. Characterization of nanoparticles was performed by employing Uv-Visible spectroscopy, Fourier-transform infrared spectroscopy, and Atomic force microscopic techniques. The size of Ful-AgNPs was found in the range from 9-18 nm. Ful-AgNPs shows selective recognition capability towards amoxicillin in the presence of other competing drugs without showing any interference. The binding ratio between Ful-AgNPs and amoxicillin was observed 1:1 (Ful-AgNPs: amoxicillin) in Jobs plot study. The sensing capability of Ful-AgNPs was also evaluated in blood plasma and tap water to evaluate the matrix effect, and Ful-AgNPs recognize amoxicillin in both mediums without showing any interferences. Fractional inhibitory concentration index shows synergistic interaction of Ful-AgNPs with amoxicillin. These results demonstrate that the combination of amoxicillin with Ful-AgNPs inhibits the growth of bacterial cells and the MIC value found to be 25-50
    Keywords: Silver nanoparticles; Antibacterial potential; UV-Visible spectroscopy; Amoxicillin; Synergistic effect; Combinatorial effect; COVID-19.