Forthcoming articles

International Journal of Nano and Biomaterials

International Journal of Nano and Biomaterials (IJNBM)

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International Journal of Nano and Biomaterials (3 papers in press)

Regular Issues

  • Physico-chemical and cytotoxic properties of capsules of nanodiamonds/ Extract of Mimosa Tenuiflora bark with chitosan in MDA-MB-231   Order a copy of this article
    by Santos Adriana Martel-Estrada, Claudia Lucía Vargas-Requena, Dulce Azucena Salazar Vazquez, José Emmanuel Sánchez-Serrano, Karen Andrea Legarreta-Arias, Imelda Olivas-Armendáriz, Carlos Alberto Martínez-Pérez, Laura Elizabeth Valencia-Gómez 
    Abstract: Cancer research is currently a biomedical concern as its worldwide incidence is estimated to be around 20 million by 2025. In this work, the synthesis of a composite of nanodiamonds/arabinogalactans of Mimosa Tenuiflora bark with chitosan is described. The morphology and physicochemical characterization of the composites were conducted using FTIR, SEM microscopy, thermogravimetric analysis (TGA), and X-ray diffraction. The cytotoxicity of the composites to breast cancer cells was evaluated. FTIR spectrum demonstrated the chemical interaction between the components, as visible in the TGA. The result suggests that chitosan predominates on the nanodiamond surface through a chemical immobilization test by solubility and X-ray diffraction analysis. The concentration of 50
    Keywords: nanodiamonds; chitosan; arabinogalactans; Mimosa Tenuiflora; FTIR; X-ray diffraction; thermal characterization; cytotoxicity; TGA; solubility.

  • Effect of Carbon Fiber Layer with Alumina and Tri calcium Phosphate on Mechanical Properties of Denture Base   Order a copy of this article
    by Wafaa A. Hussain 
    Abstract: Preparation of denture base with high mechanical properties and good aesthetic is a great demand. In this study unreinforced and reinforced samples with uncoated and coated woven carbon fibers (WCF) with alumina Al2O3 and Tri calcium phosphate (TCP) powders were incorporated into heat polymerized polymethyl methacrylate (PMMA) denture base resin in addition to poly vinyl alcohol (PVA) with 0.02 and 0.09 weight fractions (wi). Impact, flexural strength and water absorption of layered denture base resin have been studied. Surface morphology of the coating layers has been examined by field emission- scanning electron microscope (FE-SEM), and the toxicity of reinforcing materials was also investigated in human blood cells. Uncoated WCF sample showed high impact and flexural strength, but it still exhibits poor aesthetic. A significant increase of the impact strength values was observed in the coated specimen when compared with the control sample, in expense of flexural strength. The results showed that the effect of TCP on impact and flexural strength values of PMMA denture base resin was higher than when using alumina particles and this could be attributed to TCP's high stiffness and resistance to fracture. Aesthetic, impact and flexural strength have improved together when PVA increased.
    Keywords: Denture base material; coated carbon fiber; impact strength; flexural strength and aesthetic.

  • Is Benzoyl peroxide detectable under physiological conditions in orthopaedic cement?   Order a copy of this article
    by Klaus Dieter Kuehn 
    Abstract: Background: Until today, benzoyl peroxide (BPO) as a potential polymethyl methacrylate (PMMA) cement allergen is the subject of controversial discussion. Question/Purposes: Few cases have been reported in literature and ought to be seen critically. To address this issue, the present study aims to determine BPO and their degradation products biphenyl (BP) and benzoic acid (BA) within hardened cement as well as their elution from cement. Methods: Six ordinary cements characterized by different BPO:DmpT ratio were chosen for the study. Subsequently, cements were tested in-vitro under destructive, physiologic and non- physiologic conditions. Results: BPO was not detectable under destructive and physiological conditions. Cements with a N, N-Dimethyl-para-toluidine (DmpT) surplus contained lower BPO, BP and BA concentrations compared to cements with BPO surplus. Conclusions: Furthermore, the ratio of DmpT:BPO had an impact on the turnover of BPO and its degradation products. Clinical Relevance: Moreover, BPO and BP elution under physiological conditions was not detectable (< 0.1
    Keywords: PMMA; Benzoyl Peroxide; Allergy; in-vitro; HPLC.