A review on Azadirachta indica (neem) plant mediated biosynthesis, characterisation and antimicrobial activity of silver nanoparticles
by Christian Kelechi Ezeh; Chibuzor Nwadibe Eze; Marie Uju Esther Dibua; Stephen Chijioke Emencheta
International Journal of Biomedical Nanoscience and Nanotechnology (IJBNN), Vol. 5, No. 1, 2024

Abstract: The increasing spread of microbial infection and increase in occurrence of pathogens resistant to multiple antimicrobial agents necessitate the quest to develop alternative antimicrobial agents. In this regard, nanoparticles technology has shown enormous potential. Research advances in the field of nanotechnology recently include the fabrication of metallic nanoparticles (MNPs) with prominent antimicrobial action against multiple-resistant pathogens. Recently, the biological synthesis of MNPs using plant based products has garnered much attention because of its competitive benefits including: eco-friendliness, single step processing, benign, non-toxicity, and cost effectiveness. The different bioactive compounds present in the various parts of plants are responsible for the reduction of metallic ions to MNPs and the subsequent capping of the formed particles. Among all the MNPs, silver nanoparticles (AgNPs) are the most promising nano-product widely used in nanomedicine. The present review describes neem plant facilitated synthesis of silver nanoparticles, characterisation and its antimicrobial activity.

Online publication date: Mon, 01-Jul-2024

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