Tumour cells and life expectancy: an exergy approach
by Izabela Batista Henriques; Silvio De Oliveira Junior
International Journal of Exergy (IJEX), Vol. 31, No. 2, 2020

Abstract: In the present work, the rate of living theory and exergy analysis are gathered to assess the effects of cancer on life expectancy. An exergy model of a cancer cell metabolism is proposed taking into account the changes in the metabolic paths. Results indicate a threefold increase in the rate of exergy metabolism of a cancer cell. Moreover, per mole of glucose, a cancer cell obtains 8.9 moles of ATP against 32 synthesised by a healthy one. However, because of the increase in the rate of glucose uptake, the metabolic routes of the tumour are less efficient but are faster. The analysis of a generic tumour progression indicates that, in the absence of treatment, survival time would be around three years. Furthermore, in case of complete removal of the tumour, every six months living with the disease would lead to a reduction of almost four years in life expectancy.

Online publication date: Mon, 02-Mar-2020

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Exergy (IJEX):
Login with your Inderscience username and password:

    Username:        Password:         

Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com