International Journal of Environment and Pollution
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International Journal of Environment and Pollution (3 papers in press)
Analysis of the combined estrogenic activity of plasticizers by Hui Zhang, Shiqi Zhen, Zhaoying Tan, Chicheng Cao, Qi Zhang, Qi Ju Abstract: Several studies have reported that plastic additives exhibit estrogenic activity and may cause adverse effects on human health. However, existing risk assessment procedures lack the capability to accurately evaluate the combined effects of plastic additives. In this study, we performed a cell proliferation assay on the MCF-7 cell line, an estrogen-sensitive human breast cancer cell, to quantify estrogenic activities of single chemicals and their mixtures. We applied biomathematical regression models to simulate toxicity of four single substances, biphenyl A (BPA), di(2-ethylhexyl)phthalate (DEHP), di-butyl phthalate (DBP) and 17 Keywords: biphenyl A; phthalates; dose-response relationship; combined effects.
Particulate matter emission prediction of Beijing's Fengtai District through the box model application and statistical analysis of spatial layout grid. by Harrison Odion Ikhumhen, Tianxin Li, Zhou XIng Chen, An Difei Abstract: The box model technique was applied to analyse the regional air quality distribution of Beijings Fengtai district. Using the IDW interpolation and spatial grid statistical method, the spatial representation of PM emission of different regions surrounding different air monitoring stations was deduced using GIS to help suggest priority regions for monitoring station installations. The results revealed that the main source of PM10 emission in the region was the industrial and commercial areas, both exhibiting values higher that the annual PM10 concentration standard (50 Keywords: spatial representation; IDW interpolation; spatial distribution; PM10 concentration; box model; monitoring station; geographic information system.
Occurrence, seasonality, and risk assessment of (anti-)estrogenic compounds in bankside groundwater in Wuchang City, China by Jian Li, Rongfang Wang, Hedan Liu, Chenglian Feng Abstract: Riverbank filtration (RBF) is widely used in drinking water supplies. This work highlights the importance of assessing the quality of bankside groundwater through evaluation of the potential health risks using recombinant estrogen receptor (ER) gene yeast assays in conjunction with a novel risk assessment approach. While none of the water samples collected from Wuchang City, China exhibited ER agonistic activity, they all demonstrated (anti-)estrogenic activity. The bioassay-derived 4-hydroxytamoxifen equivalents (HTQs) ranged from 0.29 g/L to 44.43 g/L, which decreased after RBF treatment. For the bankside groundwater samples, the HTQ values were higher during the rainy season than during any other season, showing that climate change has the potential to affect the quality of bankside groundwater. A risk assessment was performed, and the results suggested that (anti-)estrogenic endocrine disruptors will have a low impact on human health. Keywords: bankside groundwater; riverbank filtration; climate change; water quality; health risk; estrogen receptor; endocrine-disrupting chemicals; recombined gene yeast assays; risk assessment.