Title: Biomedical applications of engineered nanoparticles in diagnosis and therapeutics

Authors: Mohammad Afzal Khan; S. Moeez

Addresses: Department of Medicine, Stanford University, VAPAHCS, 3801 Miranda Avenue, Building 101, Room B4-105, Palo Alto, California 94304, USA ' National Chemical Laboratory, Dr. Homi Bhaba Road, Pune – 411008, India

Abstract: Nanoparticles are essentially tiny pieces of material that measure no more than an atom or two across. Because of their small size, they can interact easily on the same level with microscopic pathogens such as bacteria or viruses. They are also adaptable enough that they can be applied in different biotechnological applications, from fine electronics to innovative medical procedures in modern biomedical science. Substantial research has been done to develop a series of bio products based on nanoparticles, some of which have been applied for public applications in medical science. Nanoparticles have been proved useful in number of applications but potential implementation of nanoparticles lies in their medical applications. Their tiny pathogen-sized proportions naturally make them key candidates for the fight against various unwanted foreign pathogens of the human body; they can be delivered intravenously directly into your bloodstream to destroy viruses and bacteria as same as T-cells of the immune system. This technology gives a much-needed boost to medical applications for major untreatable diseases. These new products provide stable, safe, and effective alternatives for working with potentially hazardous biological for applications such as drug targeting, immunological studies, biosensor development, and biocatalysis.

Keywords: nanoparticles; antibodies; nanoparticle conjugates; drug delivery; biomarkers; cancer diagnosis; biosensors; biomedical applications; therapeutics; nanotechnology; biocatalysis.

DOI: 10.1504/IJIS.2012.051233

International Journal of Immunological Studies, 2012 Vol.1 No.4, pp.319 - 328

Published online: 30 Aug 2014 *

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