Title: The role of genomic DNA and introns in gene transfer

Authors: Assem Mohamed M. Ali

Addresses: Genetic Engineering Research Institute, Mubarak City of Scientific, Researches and Technological Applications, Alexandria, Egypt

Abstract: This paper deals with the advantages of using genomic DNA from developed organs in gene transfer and the production of transgenic organisms. It also discusses the role of introns, the functional genes and how they are integrated into the host genomic. The integrated unfunctional DNA never causes defects or deleterious effects but on the contrary it causes repair and heterosis. The utilisation of vectors especially viruses are completely avoided.

Keywords: genomic DNA; introns; gene transfer; transgenic organisms; no vectors.

DOI: 10.1504/IJBT.2001.000174

International Journal of Biotechnology, 2001 Vol.3 No.3/4, pp.411-418

Published online: 13 Jul 2003 *

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