Title: Preparation of reduced graphene oxide/nano hydroxyapatite nanocomposite scaffold and its adoption in sports fracture injury

Authors: Danya Yang; Jianfang Wang; Jianquan Yang; Danya Fu

Addresses: Department of Physical Education, Shangluo University, Shangluo, 726200, Shaanxi, China ' Department of Chemical Engineering and Modern Materials, Shangluo University, Shangluo 726000, Shaanxi, China ' Department of Sports, Xi'an Medical University, 710021, Xi'an, Shaanxi, China ' Department of English, Shangluo University, Shangluo, 726200, Shaanxi, China

Abstract: This paper aimed to study the preparation of nanocomposite scaffold composed of reduced graphene oxide (RGO) and nano hydroxyapatite (nHA), and its adoption value in sports fracture injury. First, graphene oxide (GO) and nHA nanocrystals were prepared, which were then combined to form RGO/nHA nanocomposites. Moreover, the physiological characteristics of the formed RGO/nHA nanocomposite in the tissues of mice were analysed, such as HE staining images. Then, the prepared nanocomposites were adopted to prepare RGO/nHA nanogel composite scaffolds, which were utilised in surgery of patients with bone injuries. The SEM image showed that the GO surface showed a change in the fold morphology from the original morphology. The TEM image showed that GO/nHAs were in the form of crystal clusters, with uneven distribution and local agglomeration. Therefore, the prepared RGO/nHA nanocomposite was non-toxic, and the RGO/nHA nanocomposite had good biocompatibility.

Keywords: nanomaterials; composite scaffolds; sports fracture injuries; reduced RGO-nHA; graphene.

DOI: 10.1504/IJNT.2022.128954

International Journal of Nanotechnology, 2022 Vol.19 No.6/7/8/9/10/11, pp.752 - 767

Received: 30 Apr 2021
Accepted: 08 Jun 2021
Published online: 13 Feb 2023 *

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