Preparation of reduced graphene oxide/nano hydroxyapatite nanocomposite scaffold and its adoption in sports fracture injury Online publication date: Mon, 13-Feb-2023
by Danya Yang; Jianfang Wang; Jianquan Yang; Danya Fu
International Journal of Nanotechnology (IJNT), Vol. 19, No. 6/7/8/9/10/11, 2022
Abstract: This paper aimed to study the preparation of nanocomposite scaffold composed of reduced graphene oxide (RGO) and nano hydroxyapatite (nHA), and its adoption value in sports fracture injury. First, graphene oxide (GO) and nHA nanocrystals were prepared, which were then combined to form RGO/nHA nanocomposites. Moreover, the physiological characteristics of the formed RGO/nHA nanocomposite in the tissues of mice were analysed, such as HE staining images. Then, the prepared nanocomposites were adopted to prepare RGO/nHA nanogel composite scaffolds, which were utilised in surgery of patients with bone injuries. The SEM image showed that the GO surface showed a change in the fold morphology from the original morphology. The TEM image showed that GO/nHAs were in the form of crystal clusters, with uneven distribution and local agglomeration. Therefore, the prepared RGO/nHA nanocomposite was non-toxic, and the RGO/nHA nanocomposite had good biocompatibility.
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