An empirical evaluation of compression techniques for genome sequences
by M. Muthulakshmi; G. Murugeswari; S.P. Raja
International Journal of Biometrics (IJBM), Vol. 13, No. 4, 2021

Abstract: Databases of biological sequences are increasing at an exponential rate due to tremendous growth of living organisms. Among all other scientific databases, the size of biological databases is in terabytes. With the advancement in sequencing technologies, each day thousands of nucleotide bases of different organisms are sequenced and submitted to the database worldwide. So, there is a need for compression of biological sequence data to reduce the space required for storage and thereby increase the transmission speed. Three existing sequence compression algorithms namely modified HuffBit, one bit compression and extended American Standard Code for Information Interchange (ASCII) compression algorithms are implemented. The DNA sequence data is obtained from National Center for Biotechnology Information (NCBI) database. The main aim of this paper is to compare and evaluate the performance of existing sequence compression algorithms. Experimental results show that modified HuffBit compress algorithm performs better with an average compression ratio of 3.8.

Online publication date: Mon, 04-Oct-2021

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Biometrics (IJBM):
Login with your Inderscience username and password:

    Username:        Password:         

Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email