Historical aspects of botulinum toxin used clinically: part II: overcoming resistance
by Andy Pickett
The Botulinum J. (TBJ), Vol. 3, No. 1, 2015

Abstract: After the extraordinary success of botulinum toxin serotype A in the 1980s to treat a wide range of spasmodic muscular conditions and movement disorders, a significant number of patients were found to stop responding to their treatments with time. When investigated, they were found to have become immune ('resistant') to the products. This second article in a series looks at the next botulinum toxin serotype used clinically after serotype A to overcome this resistance and how that choice was made.

Online publication date: Thu, 04-Aug-2016

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