Title: Synthesis and characterisation of rutin-calcium

Authors: Ya-ling Jiang; Qiu-wei Liu; Guang-yu Zhai

Addresses: School of Pharmacy, Zhengzhou University of Industrial Technology, Zhengzhou, 451100, China ' School of Pharmacy, Zhengzhou University of Industrial Technology, Zhengzhou, 451100, China ' School of Pharmacy, Zhengzhou University of Industrial Technology, Zhengzhou, 451100, China

Abstract: Rutin and calcium acetate at 86°C, pH = 8.5, reflux 6h, A rutin-ca complex was synthesised in methanol. UV-Vis spectroscopy: band I shifted from 355 nm to 359 nm, red shifted to 4 nm. Band II moved from 257 nm to 266 nm and shifted red by 9 nm. IR: the absorption peak of ruthenium is broadened, υ_C = _O 1,632.45 cm⁻¹, red shift of 23 cm⁻¹, the characteristic absorption peak of benzene ring has not changed, and the absorption peak of 618.43 cm⁻¹, metal coordination bond υ_Ca-O stretching vibration peak. ¹H-NMR: 3'-OH and 4'-OH hydroxyl groups disappear, showing coordination with calcium ions. Thermal analysis showed rutin with ane calcium ion complex.

Keywords: flavonoid; rutin-calcium; complex; synthesis; spectroscopic; characterisation.

DOI: 10.1504/IJNM.2018.093471

International Journal of Nanomanufacturing, 2018 Vol.14 No.3, pp.207 - 218

Received: 05 May 2017
Accepted: 20 Oct 2017
Published online: 26 Jul 2018 *

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