Title: Affinity-based biosensors for pathogenic bacteria detection

Authors: Riccarda Antiochia; Gabriele Favero; Marcelo Enrique Conti; Franco Mazzei; Cristina Tortolini

Addresses: Dipartimento di Chimica e Tecnologie del Farmaco Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy ' Dipartimento di Chimica e Tecnologie del Farmaco Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy ' Dipartimento di Management, Sapienza Università di Roma, Viale del Castro Laurenziano 9, 00161 Rome, Italy ' Dipartimento di Chimica e Tecnologie del Farmaco Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy ' Dipartimento di Chimica e Tecnologie del Farmaco Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy; Dipartimento di Chimica, Sapienza Università di Roma, Piazzale Aldo Moro 5, 00185 Rome, Italy

Abstract: Bacteria are widely presented in any ecosystem, some of them are potentially harmful. In this context, detection of pathogenic bacteria in water, food and air is of great importance for human and environmental health. Although traditional microbiological methods are available, they are labour intensive and require well-trained personnel. To overcome these drawbacks, research directs to the development of efficient tools that offer precision, sensitivity, rapidity and ease of operation in situ. Biosensors appear as excellent analytical devices alternative or complementary to conventional methods. In this paper, we focus, in particular, on affinity based-biosensors divided on the basis of the method of signal transduction. This review covers several papers putting in evidence the improvement reached in this field of research.

Keywords: affinity biosensors; pathogenic bacteria; signal transduction; environmental analysis; food analysis; electrochemical; optical; gravimetric; environmental technology.

DOI: 10.1504/IJETM.2015.071140

International Journal of Environmental Technology and Management, 2015 Vol.18 No.3, pp.185 - 206

Accepted: 29 Dec 2014
Published online: 13 Aug 2015 *

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