Title: Single vs. multi-lead performance of the Poincaré mapping method for T wave alternans detection

Authors: Aruna Deogire; Satish Tukaram Hamde

Addresses: MET Institute of Engineering, Nashik, Maharashtra, India ' Department of Instrumentation Engineering, SGGS Institute of Engineering and Technology, Vishnupuri, Nanded, Maharashtra, India

Abstract: Detection of T wave Alternans (TWA), a risk stratification parameter for sudden cardiac death, is a continuously evolving research area. Most of the current detection approaches are single-lead approaches. This gives lead-dependent results and the alternans magnitude is either overestimated or underestimated. In this paper, a multi-lead PCA approach is suggested to improve the performance of existing single-lead methods. An implementation is carried out using the Poincaré mapping method on 30 records of the TWA challenge database. Single-lead vs. multi-lead results are studied. An improved performance of the proposed approach, in both qualitative and quantitative aspect, is observed when compared to all single leads under analysis. A detection rate of 70% and Root Mean Square Error (RMSE) of 14% are obtained for the multi-lead approach. The results are also compared with the standard MMA method, showing significant correlation of 0.96% between the two.

Keywords: multi-lead PCA; principal component analysis; Poincaré mapping; TWA; T wave alternans; SCD; sudden cardiac death; ventricular arrhythmia; heart rate variation.

DOI: 10.1504/IJBET.2015.070573

International Journal of Biomedical Engineering and Technology, 2015 Vol.18 No.3, pp.240 - 253

Received: 08 Nov 2014
Accepted: 10 Feb 2015

Published online: 10 Jul 2015 *

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