Title: Early diagnosis of LV diastolic dysfunction for diabetic patients

Authors: Manjusha Joshi; K.D. Desai; M.S. Menon

Addresses: Department of Electronics and Telecommunication, MPSTME, NMIMS University, Mumbai, India ' Maharshi Parshuram College of Engineering, Mumbai University, Velneshwar, India ' Cardiology Department, Fortis S.L. Raheja Hospital, Mahim (W), Mumbai, India

Abstract: Left ventricular diastolic dysfunction precipitates to cardiac disorders like myocardial infarction, left ventricular hypertrophy and cardiac artery disease. Raised diastolic left ventricular pressure results in inefficient pumping of the oxygenated blood, leads to LVDD modifying the heart structurally and functionally. An index computed from R-R interval, derived from two-lead, 3-5 minute ECG samples, provides a guideline to the echo-cardiologist. The index values of the diabetic subjects with LVDD are observed to be the lowest, that of diabetic subjects without LVDD are lower than the control group. The index proves to be early, safe, deployable, cost-effective and non-invasive confirmative diagnostic tool.

Keywords: myocardial ischaemia; myocardial infarction; LVDD; left ventricular diastolic dysfunction; nonlinear HRV tool; heart rate variability; Poincaré plot; standard descriptor; early diagnosis; diabetics; diabetes; left ventricular hypertrophy; cardiac artery disease; heart disease; ECG; electrocardiograms.

DOI: 10.1504/IJBET.2014.059670

International Journal of Biomedical Engineering and Technology, 2014 Vol.14 No.3, pp.233 - 242

Received: 29 Aug 2013
Accepted: 17 Jan 2014
Published online: 16 Oct 2014 *

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