Title: Design, analysis and fabrication of customised bone scaffold using RP technology

Authors: S. Rashia Begum; G. Arumaikkannu

Addresses: Department of Mechanical Engineering, College of Engineering, Anna University, Chennai 600 025, Tamil Nadu, India ' Department of Manufacturing Engineering, College of Engineering, Anna University, Chennai 600 025, Tamil Nadu, India

Abstract: Bio Additive Manufacturing (BAM), an interdisciplinary field of Rapid Manufacturing (RM) and Tissue Engineering (TE), aims to manufacture the customised bone scaffold for bone replacement. The hydrodynamic stress induced in cells will depend not only on the culture medium flow rate, but also on the scaffold three- dimensional micro-architecture. This paper presents design of the customised bone scaffolds with pore size of 0.8 mm and distance between adjacent edges of pores from 0.6 mm to 1 mm directly from the patient's CT scan data. The porosities of five customised bone scaffolds are determined. The above customised bone scaffolds are analysed in CFD software (ANSYS CFX) for the fluid density 1000 kg/m³ and viscosity 8.2 × 10⁻⁴ kgm⁻¹ s⁻¹. The estimated Wall Shear Stress (WSS) at fluid velocities from 0.2 mm/s to 1 mm/s lies in the range of 5.43 × 10⁻⁴ Pa to 36.6 × 10⁻⁴ Pa, and these scaffolds are fabricated in Rapid Prototyping (RP) technique.

Keywords: rapid prototyping; bone scaffolds; pore size; porosity; WSS; wall shear stress; CFD; computational fluid dynamics; bio-additive manufacturing; rapid manufacturing; tissue engineering; bone replacement; bone implants; bioengineering; biomechanical engineering.

DOI: 10.1504/IJCAT.2013.055329

International Journal of Computer Applications in Technology, 2013 Vol.47 No.4, pp.364 - 369

Published online: 02 Dec 2013 *

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