Title: SVM-based characterisation of liver cirrhosis by singular value decomposition of GLCM matrix

Authors: Jitendra Virmani; Vinod Kumar; Naveen Kalra; Niranjan Khandelwal

Addresses: Biomedical Instrumentation Laboratory, Department of Electrical Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India ' Department of Electrical Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India ' Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India ' Department of Radiodiagnosis and Imaging, Post Graduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012, India

Abstract: Early diagnosis of liver cirrhosis is essential as cirrhosis is an irreversible disease most often seen as precursor to development of hepatocellular carcinoma. Early diagnosis helps radiologist in better disease management by adequate scheduling of treatment options. In the present work, features derived from GLCM mean matrix, GLCM range matrix and singular value decomposition of GLCM matrix have been used along with SVM classifier for designing an efficient computer-aided diagnostic system to characterise normal and cirrhotic liver. The study has been carried out on 120 regions of interest (ROIs) extracted from 31 clinically acquired B-mode liver ultrasound images. It is observed that the first four singular values obtained by singular value decomposition of GLCM matrix result in highest accuracy and sensitivity of 98.33% and 100%, respectively. The promising results obtained by the proposed computer-aided diagnostic system indicate its usefulness to assist radiologists in diagnosis of liver cirrhosis.

Keywords: liver cirrhosis; B-mode ultrasound images; Fisher discriminant ratio; divergence; Bhattacharyya distance; singular value decomposition; SVD; support vector machines; SVM classifiers; computer-aided diagnostics; early diagnosis; grey level co-occurrence matrix; GLCM features; medical imaging; radiology.

DOI: 10.1504/IJAISC.2013.053407

International Journal of Artificial Intelligence and Soft Computing, 2013 Vol.3 No.3, pp.276 - 296

Available online: 18 Apr 2013 *

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