Article: Synthesis and characterisation of magnetic Fe2O3/Au core/shell nanoparticles for biomedical applications Journal: International Journal of Nanoparticles (IJNP) 2012 Vol.5 No.4 pp.279 - 299 Abstract: The present work details the preparation of core-shell Fe2O3@Au nanoparticles via iterative hydroxylamine seeding, which results in nanoparticles of controllable sizes ranging from 14.8 to 15.6 nm diameter. The properties of the synthesised nanoparticles were investigated by several techniques. XRD studies show that the nanoparticles have mixed two crystalline phases of α-Fe2O3 and γ-Fe2O3. The elemental analysis of the synthesised nanoparticles consists of Fe2O3 core and Au shell. VSM measurements ascertain that the synthesised nanoparticles having diameter d ≤ 16 nm show superparamagnetic behaviour at room temperature whereas with diameter d > 16 nm show hysteresis behaviour. Mossbauer studies exhibit the super-paramagnetic behaviour of sextet, doublet and Fe3+ charge state of the synthesised sample. Impedance studies of the sample exhibit a high resistance (≥ 105 Ω), which confirms the mixed phases. Thus, the synthesised nanoparticles show controllable grain size, shape, texture and magnetic properties, which finds as a suitable candidate for many biomedical applications. Inderscience Publishers - linking academia, business and industry through research

Title: Synthesis and characterisation of magnetic Fe₂O₃/Au core/shell nanoparticles for biomedical applications

Authors: K. Ravichandran; Damodaran Nedumaran

Addresses: Department of Nuclear Physics, University of Madras, Maraimalai Campus, Guindy, Chennai-600025, TN, India. ' Central Instrumentation and Service Laboratory, University of Madras, Maraimalai Campus, Guindy, Chennai-600025, TN, India

Abstract: The present work details the preparation of core-shell Fe₂O₃@Au nanoparticles via iterative hydroxylamine seeding, which results in nanoparticles of controllable sizes ranging from 14.8 to 15.6 nm diameter. The properties of the synthesised nanoparticles were investigated by several techniques. XRD studies show that the nanoparticles have mixed two crystalline phases of α-Fe₂O₃ and γ-Fe₂O₃. The elemental analysis of the synthesised nanoparticles consists of Fe₂O₃ core and Au shell. VSM measurements ascertain that the synthesised nanoparticles having diameter d ≤ 16 nm show superparamagnetic behaviour at room temperature whereas with diameter d > 16 nm show hysteresis behaviour. Mossbauer studies exhibit the super-paramagnetic behaviour of sextet, doublet and Fe³⁺ charge state of the synthesised sample. Impedance studies of the sample exhibit a high resistance (≥ 10⁵ Ω), which confirms the mixed phases. Thus, the synthesised nanoparticles show controllable grain size, shape, texture and magnetic properties, which finds as a suitable candidate for many biomedical applications.

Keywords: core-shell magnetic nanoparticles; gold nanoparticles; gold coating; Fe2O3@Au; iron oxide nanoparticles; ferric oxides; X-ray diffraction; iterative hydroxylamine seeding; vibrating sample magnetometer; VSM; biomedical applications; nanotechnology.

DOI: 10.1504/IJNP.2012.049906

International Journal of Nanoparticles, 2012 Vol.5 No.4, pp.279 - 299

Received: 19 May 2011
Accepted: 05 Sep 2011
Published online: 20 Aug 2014 *

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Title: Synthesis and characterisation of magnetic Fe2O3/Au core/shell nanoparticles for biomedical applications

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Title: Synthesis and characterisation of magnetic Fe₂O₃/Au core/shell nanoparticles for biomedical applications