Title: Evaluation of heart work as a prediagnostic tool using the modified Windkessel model and different whole blood viscosity models

Authors: S.H. Suh; Y. Kaptan; H.W. Roh; H.M. Kwon; B.K. Lee

Addresses: Department of Mechanical Engineering, Soongsil University, 511 Sangdo-dong, Dongjak-gu, Seoul, 156-743, Korea. ' Department of Mechanical Systems Engineering, Hansung University, 116 Samseongoro-16gil, Seongbuk-gu, Seoul, 136-792, Korea. ' IVAI Inc., Add 606, Wooree Venture Town, 684-02, Deungchon-dong, Gangseo-gu, Seoul, 157-754, Korea. ' Division of Cardiology, Department of Internal Medicine, Heart Center, Gangnam Severance Hospital, 211 Eonju-ro, Gangnam-gu, Seoul, 135-720, Korea. ' Division of Cardiology, Department of Internal Medicine, Heart Center, Gangnam Severance Hospital, 211 Eonju-ro, Gangnam-gu, Seoul, 135-720, Korea

Abstract: The cardiovascular diseases, especially atherosclerosis, rated among the top mortality reasons and its significance has been increasing progressively. Therefore, having a diagnostic tool to predict the cardiovascular diseases is prominent. The most common diagnostic tool for this type of disorders is using angiography; however, evaluating the Work of Heart is emerging as an easy to use and non-invasive tool recently. In this study, the modified Windkessel model and different whole blood viscosity models (Casson and Herschel-Bulkley) are employed to evaluate the heart work. The results revealed that both of the viscosity models can be used in conjunction with the modified Windkessel model.

Keywords: Windkessel model; Casson model; Herschel-Bulkley model; heart work; pre-diagnostic tools; whole blood viscosity; cardiovascular diseases; atherosclerosis; modelling.

DOI: 10.1504/PCFD.2012.048252

Progress in Computational Fluid Dynamics, An International Journal, 2012 Vol.12 No.4, pp.302 - 308

Published online: 30 Jul 2012 *

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