Title: Surface modification and characterisation of natural polymers for orthopaedic tissue engineering: a review

Authors: Mahesh Kumar Sah; Krishna Pramanik

Addresses: Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, Orissa, India ' Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Rourkela 769008, Orissa, India

Abstract: Tissue engineering has emerged as a permanent solution to treat people suffering from severe pain because of tissue loss and damage. In this technique, the key challenge is the development of scaffold with desirable characteristics like mechanical strength, biomimic properties and surface characteristics. Natural polymers are more biocompatible and induce mineralisation of bone/cartilage tissue as compared to the commonly used synthetic polymers (e.g., PLA and PLGA). This paper describes the various types of natural biopolymers for the development of tissue engineered scaffolds, mode of applications, surface modification and characterisation. A combination of modification and analysis techniques ensures better interpretation of results.

Keywords: surface modification; natural polymers; scaffold; orthopaedic tissue engineering; surface analysis; scaffold development; natural biopolymers; characterisation; biomedical engineering.

DOI: 10.1504/IJBET.2012.047744

International Journal of Biomedical Engineering and Technology, 2012 Vol.9 No.2, pp.101 - 121

Received: 08 May 2021
Accepted: 12 May 2021

Published online: 09 Jul 2012 *

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