Title: Application and performance analysis of a two-pulse synthesis model on Photoplethysmograph signals of diabetic subjects

Authors: Dharitri Goswami; Koel Chaudhury; Jayanta Mukherjee

Addresses: B.C. Roy Technology Hospital, Indian Institute of Technology, Kharagpur 721302, India. ' Indian Institute of Technology, School of Medical Science and Technology, Kharagpur 721302, India. ' Department of Computer Science and Engineering, Indian Institute of Technology, Kharagpur 721302, India

Abstract: Diabetes mellitus is a well-studied metabolic disease related to insulin deficiency that leads to high risk of cardiovascular diseases. This paper presents a non-invasive, preventive approach to measure arterial parameters from photoplethysmograph (PPG) signals of diabetic subjects. A recently proposed Two Pulse Synthesis (TPS) model (Goswami, 2010) has been used to measure Pulse Wave Velocity (PWV) of one group of 25 diabetic subjects without hypertension and another group of 45 diabetic subjects with hypertension. Results, presented through tables and figures, indicate appreciable changes in several TPS model-derived parameters due to diabetes and increase in PWV compared to normal subjects.

Keywords: diabetes; hypertension; PWV; pulse wave velocity; PPG; photoplethysmographs; TPS model; foot-to-foot delay; DPS; differential pulse spread; SDR; spread-delay ratio; arterial parameters; signal processing.

DOI: 10.1504/IJBET.2011.043301

International Journal of Biomedical Engineering and Technology, 2011 Vol.7 No.3, pp.291 - 313

Published online: 21 Jan 2015 *

Full-text access for editors Full-text access for subscribers Purchase this article Comment on this article