Title: Design and analysis of nanowire sensor array for prostate cancer detection

Authors: S.M. Ushaa, M. Madhavilatha, G. Madhusudhan Rao

Addresses: Flat no: 201, Sri Sai Enclave, New Indira Nagar, Adjacent to SGS Arts College, Tirupathi-517501, Andhra Pradesh, India. ' JNTU Hyderabad, Kukatpally, Hyderabad-500085, Andhra Pradesh, India. ' 303, MK Sun Rise Housing Board Apartments, PM Palem, Visakhapatnam-530041, Andhra Pradesh, India

Abstract: Prostate cancer is one of the major cancer affecting men in India. After lung cancer, prostate cancer has caused large number of deaths in India. Nanowire is the biosensor used for detection of cancer. In this paper, we present a design of nanowire array sensor for prostate cancer detection. A sensor array of 8 × 8 elements is designed to capture the PSA present in the blood that helps in detecting the presence of prostate cancer. An experimental setup has been developed using the biosensors lab from Nanohub.org. Based on the experimental setup the nanowire sensor is characterised for PSA detection. The sensitivity of detection is increased by use of sensor array.

Keywords: nanobiosensors; nanowires; nanosensors; biosensors; prostate cancer; cancer detection; sensor models; MATLAB; Nanohub; prostate-specific antigen; PSA; DNA; target molecules; sensor arrays; India.

DOI: 10.1504/IJNBM.2011.042132

International Journal of Nano and Biomaterials, 2011 Vol.3 No.3, pp.239 - 255

Received: 15 Nov 2010
Accepted: 13 Jan 2011
Published online: 28 Nov 2014 *

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