Title: Numerical simulations of haemodynamic factors and hyperelastic Circumferential Strain/Stress in the ideal and healthy-patient-specific carotid bifurcations for different rheological models

Authors: Mostafa Toloui, Ali Nikparto, Bahar Firoozabadi, Mohammad S. Saidi

Addresses: Department of Mechanical Engineering, Sharif University of Technology, Azadi Ave., Tehran, P.O. Box 11155-9567, Iran. ' Department of Mechanical Engineering, Sharif University of Technology, Azadi Ave., Tehran, P.O. Box 11155-9567, Iran. ' Department of Mechanical Engineering, Sharif University of Technology, Azadi Ave., Tehran, P.O. Box 11155-9567, Iran. ' Department of Mechanical Engineering, Sharif University of Technology, Azadi Ave., Tehran, P.O. Box 11155-9567, Iran

Abstract: To explore the role of hemodynamic in the initiation and progression of stenosis in carotid artery bifurcation, a Computational Fluid Dynamics (CFD) technique is applied. The effect of four rheology models is investigated as well as various mechanical phenomena. In this study, a Finite Element Method (FEM) was applied to simulate the physiologic Circumferential Strain/Stress (CS) Meanwhile, to investigate the role of vessel wall flexibility, a Fluid-Structure Interaction (FSI) analysis was applied. It was concluded that velocity profiles and WSS show sensitivity to arterial wall stiffening while shear thinning models do not have a dominant effect on the flow field.

Keywords: carotid artery bifurcation; CFD; computational fluid dynamics; FSI; fluid-structure interaction; Newtonian; non-Newtonian; WSS; wall shear stress; circumferential strain; circumferential stress; haemodynamics; rheological models; modelling; rheology; simulation; finite element method; FEM; vessel wall flexibility; arterial wall stiffening; shear thinning; blood flow; arterial pressure.

DOI: 10.1504/IJBET.2011.041776

International Journal of Biomedical Engineering and Technology, 2011 Vol.6 No.4, pp.387 - 412

Published online: 21 Jan 2015 *

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