Title: Computational haemodynamic model for study of calculated mitral valve area

Authors: J. Bustamante, M. Vallverdu, X. Borras

Addresses: Cardiovascular Dynamics Research Group, Pontificia Bolivariana University, Circular 1 No. 70–01, Ed. 7; A.A. 56006, 050022, Colombia. ' Centre de Recerca en Enginyeria Biomedica, Universitat Politecnica de Catalunya, Spain. ' Departament of Cardiology, Hospital de la Santa Creu i Sant Pau, Spain

Abstract: Simulated experience was performed through a computational haemodynamic model, with the implementation of a cardiovascular numerical model in which the dynamics of the transmitral flow is represented. The influence of haemodynamic variables are evaluated upon the calculated Mitral Valve Area (MVA) using the method of Gorlin|s formula. By sensitivity analysis of haemodynamic variables, it is found that blood density, cardiac output, length of valvular tunnel, heart rate and compliance are variables influencing the determination of the calculated MVA. In conclusion, the computational haemodynamic model helps to evaluate the isolated influence of haemodynamic parameters on the functional calculated MVA.

Keywords: cardiovascular modelling; numerical modelling; mitral valve area; computational haemodynamics; simulation; blood flow; blood density; cardiac output; valvular tunnel; heart rate.

DOI: 10.1504/IJBET.2011.039196

International Journal of Biomedical Engineering and Technology, 2011 Vol.5 No.2/3, pp.157 - 174

Published online: 21 Jan 2015 *

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