Title: Clinical significance of low-dose radiation therapy: radiation hormesis

Authors: Masao Takatori, Sadao Hattori, Makoto Yagi

Addresses: Takatori Clinic of Internal Medicine, 13-6, Yagami, Saiwai-ku, Kawasaki City, Kanagawa 212-0056, Japan. ' Central Research Institute of Electric Power Industry (CRIEPI), 97-1, Takamine-cho, Showa-ku, Nagoya-city, Aichi 466-0811, Japan. ' Lead and Company Co., Ltd., 3-71, Hie-cho, Minami-ku, Yokohama City, Kanagawa 232-0011, Japan

Abstract: This study was designed to investigate the clinical significance of low-dose radiation therapy, radiation hormesis, and accuracy of therapeutic regimen. Radiation hormesis was performed in six patients (four patients with malignant diseases and two patients with benign diseases) in the experimental room where they could be exposed to a low level of direct gamma ray and inhale radon gas (radon-222). No significant side-effect was found in any patient during the clinical course. Biopositive effects could be observed regardless of malignant or benign background. Our study result suggested that radiation hormesis should be recognised as one of the alternative treatments for cancer. The definition of low-dose radiation therapy and the standardisation of its specification and therapeutic regimen are thus called for.

Keywords: alternative treatments; superoxide dismutase; carcinogenic inhibitor p53; radiation hormesis; low-dose radiation therapy; low radiation; cancer treatment.

DOI: 10.1504/IJLR.2010.037672

International Journal of Low Radiation, 2010 Vol.7 No.6, pp.511 - 519

Available online: 23 Dec 2010 *

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