Title: Quantifying blood glucose in the non-invasive approach

Authors: J. Sundararajan, Mandyam Sandeep, V. Palanisamy

Addresses: Department of ECE, Paavai Engineering College, Salem-Namakkal Highways (NH-7), Paavai Nagar, Pachal, Namakkal-637018, Tamil Nadu, India. ' Department of ECE, Paavai Engineering College, Salem-Namakkal Highways (NH-7), Paavai Nagar, Pachal, Namakkal-637018, Tamil Nadu, India. ' Info Institute of Engineering, Sathy Road, Kovilpalayam, Coimbatore – 641107, India

Abstract: Diabetes mellitus is considered as one of the rapidly swelling disorders around the globe. Currently, the HbA1c or glycated hemoglobin (Chandalia and Krishnaswamy, 2002) test (invasive) is most preferred for glucose quantification. Here, we present a novel framework for blood glucose level measurement using a combination of HbA1c test and stable, accurate photo acoustic (PA) methods to get an absolutely consistent and precise, non-invasive technique. A pulsed laser diode is the source. The detector setup consists of a ring detector including two double ring sensors which are attached to the ring shaped module worn around the finger. The results obtained in this research have been studied and analysed by comparing these with that of in vitro techniques like the HPLC. The comparison between the two results has been plotted and it shows a least error. The results also show a positive drive for using this concept as a basis for future extension in quantifying the other blood components.

Keywords: blood glucose levels; glycated hemoglobin test; pulsed repetition frequency; pulsed laser diodes; double ring sensors; direction sensitivity; blood glucose measurement; photoacoustic methods; non-invasive testing.

DOI: 10.1504/IJMEI.2010.035217

International Journal of Medical Engineering and Informatics, 2010 Vol.2 No.3, pp.219 - 246

Published online: 14 Sep 2010 *

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