Title: Sequence alignment and phylogenetic analysis of Human Herpes Simplex Virus (HHV) using bioinformatics tool: a review

Authors: Vipan Kumar Sohpal, Apurba Dey, Amarpal Singh

Addresses: Department of Chemical and Biotechnology, Beant College of Engineering and Technology, Gurdaspur, Punjab 143 521, India. ' Department of Biotechnology, National Institute of Technology, Durgapur, West Bengal, India. ' Department of Electronics and Communication Engineering, Beant College of Engineering and Technology, Gurdaspur, Punjab 143 521, India

Abstract: Bioinformatics is the application of computational techniques to analyse the wet lab information associated with biomolecules on a commercial scale. Today|s it concentrate on structural biology, genomics to gene expression studies. In this review we discuss the main principles that desirable bioinformatics analyses, sequence alignment and phylogenetic analysis from biological databases that are commonly used and examine some of the studies that are being conducted, particularly with reference to Human Herpes Simplex Virus (HHV). Finally provide an introduction and overview of the bioinformatics tools and software used for sequence alignment.

Keywords: bioinformatics; sequence alignment; phylogenetic analysis; biological databases; human herpes simplex virus; HHV.

DOI: 10.1504/IJCBDD.2010.034466

International Journal of Computational Biology and Drug Design, 2010 Vol.3 No.1, pp.68 - 88

Published online: 05 Aug 2010 *

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