Title: Study on the effect of different shaped stenoses on blood flow through coronary artery

Authors: D.K. Mandal, S. Chakrabarti

Addresses: Department of Basic Science and Humanities, College of Engineering and Management, Kolaghat, P.O.: K.T.P.P. Township, Midnapore (E) 721 171, West Bengal, India. ' Department of Mechanical Engineering, Bengal Engineering and Science University, Shibpur, Howrah 711 103, West Bengal, India

Abstract: A numerical study has been carried out to investigate disturbances of blood flow through coronary artery with different shaped restrictions. From this study, it is revealed that pressure drop and vortex size is more for sharp edged stenosis, whereas wall shear stress rise is more in case of smooth shaped stenosis. The physiological impact on initiation and progression of disease of artery due to pressure drop increases with stricture length but impact due to peak wall shear stress decreases with stricture length for any shaped restrictions. Mathematical models are developed to predict extent of blockage and, corresponding reattachment length and wall shear stress rise for all shaped restrictions.

Keywords: restriction percentage; stricture length; Reynolds number; wall pressure; WSS; wall shear stress; stenoses; stenoisis shape; blood flow; coronary artery; pressure drop; vortex size; physiological impact; mathematical modelling; blockage; reattachment length.

DOI: 10.1504/IJBET.2010.034274

International Journal of Biomedical Engineering and Technology, 2010 Vol.4 No.1, pp.1 - 17

Published online: 31 Jul 2010 *

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