Title: Electrochemically deposited metal nanoparticles for enhancing the performance of microfluidic MEMS in biochemical analysis

Authors: Abdulilah Dawoud Bani-Yaseen, Toshikazo Kawaguchi, Ryszard Jankowiak

Addresses: Department of Chemistry, Taibah University, Al-Madinah Al-Munawarah, KSA. ' Arts, Science and Technology Center for Cooperative Research, Kyushu University, Kasuga-shi, Fukuoka, 816-8580, Japan. ' Department of Chemistry, Kansas State University, Manhattan, KA 66502, USA

Abstract: The fabrication and evaluation of the analytical performance of integrated microfluidic MEMS modified with electrochemically deposited metal nanoparticles are described in this paper. The microfluidic MEMS is a hydride system that comprise two layers, poly-dimethylsiloxane (PDMS) and glass, which in turn enclose a micro channels network and a set of 15 micro electrodes, respectively. The mechanism of electrokinetic phenomenon and electrochemical detection were applied for performing injection and separation, and sensing the components of a biochemical mixture, respectively. The technique of electrochemical deposition was employed for depositing nanoparticles of gold, palladium and platinum on the surface of integrated microelectrodes. The nanoparticles-modified micro electrodes were characterised electrochemically and using scanning electron microscope (SEM). Importantly, the nanoparticles-based decoupler has significantly enhanced the analytical performance of the microfluidic MEMS, where detection limits in the low nanomolar range were recorded for the targeted analytes.

Keywords: metal nanoparticles; microfluidics; biochemical analysis; microelectromechanical systems; MEMS; electrochemistry; integrated devices; capillary electrophoresis; neurotransmitters; DNA adduct; electrokinetics; gold; palladium; platinum; nanotechnology.

DOI: 10.1504/IJNM.2009.028116

International Journal of Nanomanufacturing, 2009 Vol.4 No.1/2/3/4, pp.99 - 107

Published online: 07 Sep 2009 *

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