Title: Reduction of doubtful detection of micro-nucleus in human lymphocyte

Authors: Domenico Grimaldi, Francesco Lamonaca

Addresses: Department of Electronics, Computer and System Sciences, University of Calabria, 87036 Rende CS, Italy. ' Department of Electronics, Computer and System Sciences, University of Calabria, 87036 Rende CS, Italy

Abstract: The image correction is proposed by evaluating the Point-Spread Function (PSF) of Wiener|s deconvolution for motion blur and Gaussian out of focus alterations. It permits to reduce the number of rejected images for the detection of Micro Nucleuses into lymphocyte images. It operates in conjunction with spatial filters, pointed out to correct bad exposure, Gaussian out of focus and noise. The heavy computation burden suggests to use the Wiener|s deconvolution to process the rejected images from spatial filters. To speed-up the correction, the implementation is based on computing distributed service. The criteria to establish the number of PCs is evaluated. This is an expanded version of a paper presented at the 3rd IEEE International Workshop on Medical Measurements and Applications, 9–10 May 2008, Ottawa, ON, Canada.

Keywords: image processing; image alteration; Wiener deconvolution; spatial filters; computing distributed services; image correction; motion blur; Gaussian out of focus; micro-nucleus; human lymphocyte; medical imaging.

DOI: 10.1504/IJAMC.2009.026853

International Journal of Advanced Media and Communication, 2009 Vol.3 No.1/2, pp.80 - 94

Published online: 27 Jun 2009 *

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