Title: Material control and accountability for laboratory biosecurity

Authors: George T. Baldwin, Susan B. Rivera, Reynolds M. Salerno

Addresses: Sandia National Laboratories, Albuquerque, NM 87185, USA. ' Sandia National Laboratories, Albuquerque, NM 87185, USA. ' Sandia National Laboratories, Albuquerque, NM 87185, USA

Abstract: Laboratory biosecurity refers to a suite of measures to protect legitimate stocks of dangerous pathogens and toxins from being acquired by individuals with malicious intent. Intentional misuse presents a different problem than accidental misuse, which is the subject of laboratory biosafety. In particular, the material control and accountability (MC&A) component of laboratory biosecurity addresses an insider threat. MC&A directly involves the personnel who work with pathogens and toxins that could be attractive to bioterrorists. Control of material comprises both procedural and physical measures for both material and MC&A-relevant information. Accountability requires a one-to-one correspondence between materials and people, together with a system of records, reporting and audit. Key elements of MC&A should be understood intellectually, rather than being applied simply as a prescriptive list of security measures. MC&A measures reflect an additional stewardship responsibility that technical people accept in working with material that could harm others if used improperly.

Keywords: biosecurity; laboratory; material control; material accountability; pathogens; security; stocks; toxins; biological security; risk assessment; biological threats; bioterrorism.

DOI: 10.1504/IJRAM.2009.025927

International Journal of Risk Assessment and Management, 2009 Vol.12 No.2/3/4, pp.368 - 379

Published online: 25 May 2009 *

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