Title: Nanostructured phospholipid membranes

Authors: Antonella Badia, Patricia Moraille, Nathalie Y-Wa Tang, Marie-Eve Randlett

Addresses: Department of Chemistry, FQRNT Center for Self-Assembled Chemical Structures, Universite de Montreal, C.P. 6128, succursale Centre-ville, Montreal, QC H3C 3J7, Canada. ' Department of Chemistry, FQRNT Center for Self-Assembled Chemical Structures, Universite de Montreal, C.P. 6128, succursale Centre-ville, Montreal, QC H3C 3J7, Canada. ' Department of Chemistry, FQRNT Center for Self-Assembled Chemical Structures, Universite de Montreal, C.P. 6128, succursale Centre-ville, Montreal, QC H3C 3J7, Canada. ' Department of Chemistry, FQRNT Center for Self-Assembled Chemical Structures, Universite de Montreal, C.P. 6128, succursale Centre-ville, Montreal, QC H3C 3J7, Canada

Abstract: This review describes a simple high-throughput method for producing laterally nanostructured monolayer and bilayer films on planar surfaces based on the Langmuir-Blodgett transfer of a phase-separated phospholipid mixture from the air/water interface to a solid support. Applications of the patterned lipid films to spatially direct the adsorption of proteins and to demonstrate stereoselective enzyme lithography are reviewed.

Keywords: phospholipid membranes; patterning; nanostructures; Langmuir monolayer films; Langmuir-Blodgett deposition; surface template; protein adsorption; stereoselective enzyme lithography; atomic force microscopy; AFM; nanotechnology; bilayer films; patterned lipid films.

DOI: 10.1504/IJNT.2008.019842

International Journal of Nanotechnology, 2008 Vol.5 No.9/10/11/12, pp.1371 - 1395

Published online: 09 Aug 2008 *

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