Title: Multiagent modelling and simulation of carbohydrate oxidation in cell

Authors: Nicola Cannata, Flavio Corradini, Emanuela Merelli

Addresses: Dipartimento di Matematica e Informatica, Universita di Camerino, Camerino 62032, Italy. ' Dipartimento di Matematica e Informatica, Universita di Camerino, Camerino 62032, Italy. ' Dipartimento di Matematica e Informatica, Universita di Camerino, Camerino 62032, Italy

Abstract: A cell consists of a large number of components interacting in a dynamic environment. The complexity of interactions among cell components makes design of cell simulation a challenging task. Multiagent systems can be considered a suitable framework for modelling and engineering complex systems organised as autonomous interactive components. The multiagent paradigm proved natural and useful not only in building simulations, but also for devising an engineering methodology. To evaluate the proposed approach, we constructed a multiagent model of cell components involved in the metabolic pathways of Carbohydrate Oxidation (CO).

Keywords: agent technology; multi-agent systems; MAS; agent-based systems; systems biology; cell simulation; complex systems; model validation; carbohydrate oxidation; cell components; metabolic pathways; multi-agent modelling.

DOI: 10.1504/IJMIC.2008.018191

International Journal of Modelling, Identification and Control, 2008 Vol.3 No.1, pp.17 - 28

Available online: 10 May 2008 *

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