Title: Efficiency oriented, hybrid approach for modelling deformable particles in three dimensions

Authors: M.M. Dupin, I. Halliday, C.M. Care, L.L. Munn

Addresses: Steele Laboratory for Cancer Biology, Massachusetts General Hospital and Harvard Medical School, Boston, USA. ' Materials and Engineering Research Institute, Sheffield Hallam University, Sheffield, UK. ' Materials and Engineering Research Institute, Sheffield Hallam University, Sheffield, UK. ' Steele Laboratory for Cancer Biology, Massachusetts General Hospital and Harvard Medical School, Boston, USA

Abstract: In this paper, we demonstrate a new, rigorous, accurate and efficient model for simulating the flow of a suspension of deformable particles. The model uses a hybrid system: an Eulerian approach is used for the Navier-Stokes solver and a Lagrangian approach for the evolution of the DPs mesh. We demonstrate in this manuscript the capabilities of the model by simulating more than 130 deformable RBC in a tube of 60 × 30 × 30 m; the transverse migration of 20 vesicles at a low concentration (25% by volume) in a capillary tube of dimensions 150 × 40 × 40 m, in a matter of hours.

Keywords: blood flow; deformable particles; DPs; emulsion; hybrid model; lattice Boltzmann method; suspension flow; vesicles; simulation.

DOI: 10.1504/PCFD.2008.018083

Progress in Computational Fluid Dynamics, An International Journal, 2008 Vol.8 No.1/2/3/4, pp.109 - 120

Available online: 30 Apr 2008 *

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