Title: Clinical applications of Titanium dental implants coated with glass-reinforced Hydroxyapatite composite (Bonelike®)

Authors: J.V. Lobato, N. Sooraj Hussain, M.A. Lopes, J.M. Lobato, A.C. Mauricio, A. Afonso, N. Ali, J.D. Santos

Addresses: CHVNG – Servico de Estomatologia, Centro Hospitalar de Vila Nova de Gaia, Gaia, Portugal; ICBAS – Instituto de Ciencias Biomedicas de Abel Salazar, Universidade do Porto, Largo Professor Abel Salazar, 2, 4099-003 Porto, Portugal; CECA/ICETA – Centro de Estudos de Ciencia Animal, Instituto de Ciencias e, Tecnologias Agrarias e Agro-Alimentares, Campus Agrario de Vairao, Rua Padre Armando Quintas, 4485-661 Vairao, Portugal. ' INEB – Instituto de Engenharia Biomedica, Laboratorio de Biomateriais, Rua Campo Alegre, 823, 4150-180, Porto, Portugal; FEUP – Faculdade de Engenharia da Universidade do Porto, DEMM, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. ' INEB – Instituto de Engenharia Biomedica, Laboratorio de Biomateriais, Rua Campo Alegre, 823, 4150-180, Porto, Portugal; FEUP – Faculdade de Engenharia da Universidade do Porto, DEMM, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. ' Faculdade de Medicina da Universidade do Porto, Al. Prof. Hernani Monteiro, 4200 – 319 Porto, Portugal. ' ICBAS – Instituto de Ciencias Biomedicas de Abel Salazar, Universidade do Porto, Largo Professor Abel Salazar, 2, 4099-003 Porto, Portugal; CECA/ICETA – Centro de Estudos de Ciencia Animal, Instituto de Ciências e, Tecnologias Agrarias e Agro-Alimentares, Campus Agrario de Vairao, Rua Padre Armando Quintas, 4485-661 Vairao, Portugal. ' FMDUP – Faculdade de Medicina Dentaria da Universidade do Porto, Rua Dr. Manuel Pereira da Silva, 4200-393 Porto, Portugal. ' Department of Mechanical Engineering, University of Aveiro, 3810-193 Aveiro, Portugal. ' INEB – Instituto de Engenharia Biomedica, Laboratorio de Biomateriais, Rua Campo Alegre, 823, 4150-180, Porto, Portugal; FEUP – Faculdade de Engenharia da Universidade do Porto, University of Porto, DEMM, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal

Abstract: Commercially pure titanium dental implants were coated with glass-reinforced hydroxyapatite composites (Bonelike®) using the plasma spraying technique. A total of 27 Bonelike® coated 3.75 mm diameter and 10 mm length implants were placed in the maxilla (18) and mandible (9) of seven patients. Pre and post-operative radiological examination was performed by orthopantomogram according to the standard follow-up protocols. After a 3-month healing period, one patient|s implant from the mandible was surgically removed due to bad positioning and was then assessed by light and scanning electron microscopy for histological analysis. The reported Bonelike® coated dental implants proved to be highly bioactive with extensive new bone formation and attachment.

Keywords: Bonelike coatings; plasma spraying; titanium dental implants; clinical application; bone regeneration; glass-reinforced hydroxyapatite composites; radiological examination; orthopantomogram; new bone formation; bioengineering.

DOI: 10.1504/IJNM.2008.017845

International Journal of Nanomanufacturing, 2008 Vol.2 No.1/2, pp.135 - 148

Published online: 19 Apr 2008 *

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