Title: Two approaches to effective ventilation system design for the biomedical device and pharmaceutical industries

Authors: Rodney G. Handy, Dave Goodman, Sean Odukomaiya, Monica Rodriguez, Michael Whitfield, Waqar Ahmed, Mark J. Jackson

Addresses: MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA. ' MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA ' MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA. ' MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA. ' MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA. ' University of Central Lancashire, School of Computing, Technology and Physical Sciences, Preston PR1 2HE, UK. ' MET, College of Technology, Purdue University, West Lafayette, IN 47907, USA

Abstract: This paper provides two alternative solutions to the difficult task of providing adequate ventilation to operations found in the biomedical device and pharmaceutical manufacturing industries. The first approach involves a two-tier strategy that includes an isolation chamber and an appropriately designed local exhaust hood. The second approach involves the design of modular, walk-in hood. Mechanical and electrical design and development criteria for each option are delineated, and advantages and limitations are elucidated for both systems. Future efforts will target the testing of these two approaches under laboratory conditions to assess the merits of each.

Keywords: microparticles; nanoparticles; nanomaterials; biomedical materials; environmental engineering; biomaterials; ventilation system design; pharmaceutical industry; biomedical devices.

DOI: 10.1504/IJNBM.2007.016518

International Journal of Nano and Biomaterials, 2007 Vol.1 No.1, pp.35 - 49

Available online: 07 Jan 2008 *

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