Title: Effect of solvents on the phytochemical extraction of Wrightia tinctoria and study of its antibacterial activity against different pathogens

Authors: Anju Radhakrishnan; M.G. Bhuvaneswary; E.C. Baiju; T.H. Gayathri

Addresses: Research and Post Graduate Department of Chemistry, Sree Narayana Mangalam (SNM) College, Maliankara, Kerala, 683516, India ' Research and Post Graduate Department of Chemistry, Sree Narayana Mangalam (SNM) College, Maliankara, Kerala, 683516, India ' Research and Post Graduate Department of Botany, Sree Narayana Mangalam (SNM) College, Maliankara, Kerala, 683516, India ' Research and Post Graduate Department of Chemistry, Sree Narayana Mangalam (SNM) College, Maliankara, Kerala, 683516, India

Abstract: In the present study the acetone, alcohol and aqueous extracts of Wrightia tinctoria, whole plant was screened for the occurrence of phytochemical components and tested for antibacterial activity against the pathogens like Escherichia coli, Klebsiella pneumonia and Staphylococcus aureus. The qualitative screening of phytochemical constituents of Wrightia tinctoria species reveals the presence of phytochemicals like alkaloids, steroids, tannins etc. The antimicrobial screening on different test pathogen using disc diffusion method disclosed potent inhibitory against E. coli, K. pneumonea and S. aures with zone of inhibition ranging from 7 mm to 31 mm. The Green synthesis of silver nanoparticle was done using the aqueous solution of leaf extract of Wrightia tinctoria. The developed silver nanoparticles were characterised by UV-VIS Spectrophotometer and its antibacterial studies were also performed.

Keywords: phytochemistry; nanotechnology; nanoparticles; green synthesis; antimicrobial activity.

DOI: 10.1504/IJNBM.2026.153228

International Journal of Nano and Biomaterials, 2026 Vol.11 No.3, pp.266 - 278

Accepted: 20 Nov 2025
Published online: 29 Apr 2026 *

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