Title: Design and analysis of microfluidic channel with W-shaped electrodes for separation of bio-particles using dielectrophoresis technique

Authors: Muktimani Brahma; R. Kumar; Trigunesh Narzary

Addresses: Department of Electronics and Instrumentation Engineering, National Institute of Technology Nagaland, Nagaland, India ' Department of Electronics and Instrumentation Engineering, National Institute of Technology Nagaland, Nagaland, India ' Department of Electronics and Instrumentation Engineering, National Institute of Technology Nagaland, Nagaland, India

Abstract: A unique microfluidic device with W-shaped electrodes is designed to separate the micro-bio-particles. The microfluidic device efficiently separates the red blood cells (RBCs) and platelets using the dielectrophoresis technique. The separation process has been analysed by using COMSOL Multiphysics software and found that the electrode with the minimum gap of 25 µm acquired optimum results at an applied voltage of 8 V. The proposed device gave a high separation efficiency of 89.5% and a separation purity of 99.63%. The enhanced microfluidic device gave better results compared to other recent works and is exceptionally suitable for separation of micro-bio-particles.

Keywords: dielectrophoresis; red blood cells; RBCs; platelets; separation; microchannel; electrodes; flow rate; electric field; non-uniform; force.

DOI: 10.1504/IJMEI.2025.149543

International Journal of Medical Engineering and Informatics, 2025 Vol.17 No.6, pp.526 - 536

Received: 24 Aug 2022
Accepted: 20 Feb 2023
Published online: 07 Nov 2025 *

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