Title: Arterial mechanical effects of fluid-structure interaction on a stenosed carotid blood pulsatile flow under pressure conditions of normal and hypertension

Authors: Md. Jashim Uddin; M.Z.I. Bangalee

Addresses: Department of Applied Mathematics, University of Dhaka, Dhaka-1000, Bangladesh; Department of Applied Mathematics, Noakhali Science and Technology University, Noakhali-3814, Bangladesh ' Department of Applied Mathematics, University of Dhaka, Dhaka-1000, Bangladesh

Abstract: A preceding pathology named atherosclerosis, the most common cardiovascular disease (CVD) involves several hemodynamic factors affecting the arterial wall endothelium cells with increasing morbidity. The fluid-structure interaction technique has been adopted for concurrently confiscating the interaction between the anatomical blood flow dynamics and the properties of wall mechanics with COMSOL multi-physics software that is employed under normal blood pressure (NBP) and high blood pressure (HBP) to detect the significant impacts on hemodynamics in a stenotic carotid artery. The present research intends to explore that von Mises stress across the artery wall has significantly increased in HBP compared to that in NBP. Results indicate that the variations of wall displacement and recirculation length occur due to the elastic model under pressure conditions. The time-averaged wall shear stress, oscillatory shear index and relative residence time suggest that the potential risk parameters due to atherosclerotic thrombus deposition have a sequentially reduced separation length with an increase of mechanical elastic modulus.

Keywords: fluid-structure interaction; FSI; mechanical elasticity; pressure gradient; recirculation length; von Mises stress; wall displacement.

DOI: 10.1504/PCFD.2025.145998

Progress in Computational Fluid Dynamics, An International Journal, 2025 Vol.25 No.3, pp.142 - 158

Received: 17 Nov 2023
Accepted: 29 Jul 2024
Published online: 01 May 2025 *

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