Title: The multifaceted applications of Al₂O₃ nanoparticles in biomedicine: a comprehensive review

Authors: Vinayakprasanna N. Hegde

Addresses: Department of Physics, Vidyavardhaka College of Engineering, Gokulum III Stage, Mysuru, 570002, India

Abstract: Aluminium oxide nanoparticles (Al₂O₃ NPs) have emerged as a promising class of nanomaterials with diverse biomedical applications. Their unique physicochemical and mechanical properties, biocompatibility, and ease of functionalisation have led to extensive research exploring their potential in various biomedical fields. This review paper comprehensively summarises the recent advances in the biomedical applications of Al₂O₃ NPs, encompassing drug delivery systems, tissue engineering, bioimaging, and diagnostic platforms, etc. The discussion focuses on the synthesis methods and surface modifications that enhance the efficacy and biocompatibility of Al₂O₃ NPs. Additionally, the review shedding light on their potential toxicological implications and biodegradability. Overall, this paper provides valuable insights into the current state of research on Al₂O₃ NPs in the biomedical domain, fostering advancements in healthcare and medical technologies.

Keywords: biomedicine; nanoparticles; Al₂O₃; toxicity.

DOI: 10.1504/IJBET.2024.140690

International Journal of Biomedical Engineering and Technology, 2024 Vol.46 No.1, pp.47 - 62

Received: 11 Dec 2023
Accepted: 10 Jan 2024
Published online: 30 Aug 2024 *

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