Title: Calibration method for mechanical accuracy of drug dissolution meter based on wavelet transform
Authors: Baihu Sun; Bo Yang; Liyuan Zhang
Addresses: Department of Food and Drug Engineering, Shijiazhuang University of Applied Technology, Shijiazhuang 050081, China ' Department of Food and Drug Engineering, Shijiazhuang University of Applied Technology, Shijiazhuang 050081, China ' Department of Food and Drug Engineering, Shijiazhuang University of Applied Technology, Shijiazhuang 050081, China
Abstract: Aiming at the problems of large mechanical accuracy calibration error in the existing mechanical accuracy calibration methods of drug dissolution meter, a mechanical accuracy calibration method of drug dissolution meter based on wavelet transform is proposed. Firstly, the internal structure and operation process of the drug dissolution meter were analysed to determine the key parameters. Then, the weight of key parameters is determined by entropy, and the parameters with higher weight are used as the calibration object. Finally, with the help of wavelet transform wavelet signal decomposition and reconstruction, the mechanical accuracy calibration model of drug dissolution instrument is constructed. The mechanical operation parameters of drug dissolution instrument are taken as the model input data, and the mechanical accuracy calibration results of drug dissolution instrument are corrected by singular value packet decomposition. The results show that the calibration error of the proposed method is less than 5%.
Keywords: wavelet transform; mechanical accuracy; calibration; singular value packet decomposition; decomposition; reconstruction; drug dissolution meter.
DOI: 10.1504/IJMTM.2023.131300
International Journal of Manufacturing Technology and Management, 2023 Vol.37 No.2, pp.126 - 137
Received: 18 Sep 2021
Received in revised form: 27 Oct 2021
Accepted: 12 Apr 2022
Published online: 06 Jun 2023 *