Title: Clinical value of injected calcium phosphate cement/recombined bone xenograft-based hybrid nano-biomaterials in the knee joint sports rehabilitation ability

Authors: Wenting Zhou

Addresses: Department of Physical Education, Xi'an University of Posts and Telecommunications, Xi'an 710121, China

Abstract: Different types of heterozygous nanomaterials, such as ICPC/RBX, ICPC/RBX+4%PLGA and ICPC/RBX+8%PLGA, were prepared based on ICPC raw materials, and their physical and chemical properties were tested. The results showed that ICPC/RBX material, ICPC/RBX + 4%PLGA material, and ICPC/RBX + 8%PLGA material could form in phosphate buffer saline (PBS), and there was no collapse. The compressive strength of ICPC/RBX + 4% PLGA (18.35 ± 2.84) and ICPC/RBX + 8%PLGA (16.87 ± 2.96) was always lower than the strength of ICPC (35.08 ± 2.13) and ICPC/RBX (34.61 ± 2.25) (P < 0.05). In conclusion, both ICPC/RBX + 4% PLGA and ICPC/RBX + 8% PLGA materials prepared in this study had good injectable property, collapsibility, and ultimate compressive strength.

Keywords: PLGA nanospheres; ICPC/RBX hybrid biomaterials; new bone formation rate; biomechanics; ultimate compressive strength; knee joint sports injury.

DOI: 10.1504/IJNT.2022.128955

International Journal of Nanotechnology, 2022 Vol.19 No.6/7/8/9/10/11, pp.522 - 538

Received: 30 Apr 2021
Accepted: 09 Jun 2021

Published online: 13 Feb 2023 *

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