Title: Graphene oxide nanomaterials in the recovery of shoulder joint movement contraction

Authors: Yayun Zhu

Addresses: Department of Physical Education, Shanghai Polytechnic University, Shanghai, 201209, China

Abstract: The drug loading capacity, the drug releasing capacity, and the antibacterial ability of the GO-TiO2 nanotubes were analysed. The results showed that after seven days of culture, the cell adhesion rate on GO-TiO2 surface (79.9%) was obviously higher than that on pure titanium surface (52%) (P < 0.05); the mesenchymal stem cells (MSCs) on GO-TiO2 nanotubes surface were in the form of polymerised colonies, while the MSCs on the surface of pure Ti were in the form of dispersed particles. The drug-loaded GO-TiO2nanotube film did not release the drug after eight days, while the drug release time of the drug-loaded GO-TiO2 nanotube film covered by poly(lactide-coglycolide) (PLGA) was extended to 24 days. The antibacterial ability of pure Ti, GO-TiO2 nanotubes, and drug-loaded GO-TiO2 nanotubes was compared as pure Ti < GO-TiO2 nanotubes<drug-loaded GO-TiO2 nanotubes. Therefore, it was very useful for monitoring the recovery of exercise contraction function.

Keywords: graphene oxide; titanium dioxide nanotube; antibacterial ability; mesenchymal stem cells; shoulder joint; recovery.

DOI: 10.1504/IJNT.2022.128951

International Journal of Nanotechnology, 2022 Vol.19 No.6/7/8/9/10/11, pp.720 - 735

Received: 30 Apr 2021
Accepted: 03 Jun 2021

Published online: 13 Feb 2023 *

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