Title: Ethanolic bark extract of Terminalia arjuna mediated biogenic silver nanoparticles and their antimicrobial and anticancer activities

Authors: Monalisa Mohanty; Bhabani S. Jena

Addresses: Environment and Sustainability Department, CSIR-Institute of Minerals and Materials Technology, Bhubaneswar – 751 013, Odisha, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad – 201 002, India ' Environment and Sustainability Department, CSIR-Institute of Minerals and Materials Technology, Bhubaneswar – 751 013, Odisha, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad – 201 002, India

Abstract: A rapid one step process was achieved for the synthesis of silver nanoparticles (AgNPs) using phenolic rich bark extract of Terminalia arjuna. Characterisation of AgNPs was performed by using different analytical tools and techniques. Synthesised AgNPs were potentially cytotoxic to human breast cancer cell line (MCF-7) in a dose and time dependent manner as assayed through MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and nuclear staining method. Further, the synthesised AgNPs were found to possess marked antimicrobial activity against bacterial strains (Escherichia coli, Salmonella typhimurium, Klebsiella pneumonia, Bacillus subtilis and Staphylococcus aureus) and one fungal strain (Aspergillus niger).

Keywords: Terminalia arjuna; silver nanoparticles; MCF-7; antimicrobial; anticancer.

DOI: 10.1504/IJNT.2021.116175

International Journal of Nanotechnology, 2021 Vol.18 No.5/6/7/8, pp.572 - 589

Published online: 12 Jul 2021 *

Full-text access for editors Full-text access for subscribers Purchase this article Comment on this article