Title: Application of 3D biological nano scaffold materials in the health treatment of foot and ankle sports

Authors: Rong Ren; Junhua Ji; Junwen Ding; Zhaowei Li; Shuaixian Tao; Zeqing Li

Addresses: Department of Orthopaedics, Affiliated Hospital of Qinghai University, XiNing, 810001, China ' Department of Laboratory, Affiliated Hospital of Qinghai University, XiNing, 810001, China ' Department of Laboratory, Affiliated Hospital of Qinghai University, XiNing, 810001, China ' Department of Laboratory, Affiliated Hospital of Qinghai University, XiNing, 810001, China ' Department of Laboratory, Affiliated Hospital of Qinghai University, XiNing, 810001, China ' Department of Laboratory, Affiliated Hospital of Qinghai University, XiNing, 810001, China

Abstract: Bone tissue is an important part of the human body and plays an indispensable physiological function. Damage to bone tissue will have a serious impact on the health of patients. Three types of MGPC scaffolds were prepared using 3D printing technology. The macroscopic, microstructure, and histology of the three scaffolds were observed under an electron microscope. The cells grew normally and spread well. Rat L-929 fibroblasts were cultured in three scaffold extracts, and the cells were cultured with DMEM as a control. Cell proliferation was detected by cell counting. Scanning electron microscopy of the cell-scaffold complex revealed that a large number of chondrocytes adhered and grew on the surface of the MGPC scaffold. With the increase of culture time, the number of cells in each group showed an increasing trend. MGPC has no cytotoxicity, excellent physical and chemical properties, and is expected to become a biological scaffold material.

Keywords: nano biological scaffold; foot and ankle; 3D printing technology; physical and chemical properties; nanotechnology.

DOI: 10.1504/IJNT.2021.114235

International Journal of Nanotechnology, 2021 Vol.18 No.1/2/3/4, pp.329 - 340

Received: 08 May 2021
Accepted: 12 May 2021

Published online: 12 Apr 2021 *

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