Title: Bone metastatic tumour minimisation due to thermal cementoplasty effect, clinical and computational methodologies

Authors: V.C.C. Oliveira; Elza M.M. Fonseca; J. Belinha; C.C. Rua; P.A.G. Piloto; R.M. Natal Jorge

Addresses: Centro Hospitalar do Porto, Institute of Biomedical Sciences Abel Salazar, University of Porto (CHP-ICBAS), Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal ' Mechanical Engineering Department, School of Engineering, Polytechnic of Porto (ISEP), Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal ' Mechanical Engineering Department, School of Engineering, Polytechnic of Porto (ISEP), Rua Dr. António Bernardino de Almeida 431, 4249-015 Porto, Portugal ' Applied Mechanics Department, LAETA INEGI – Polytechnic of Institute of Bragança (IPB), Campus de Sta Apolónia, 5300-253 Bragança, Portugal ' Applied Mechanics Department, LAETA INEGI – Polytechnic of Institute of Bragança (IPB), Campus de Sta Apolónia, 5300-253 Bragança, Portugal ' Mechanical Engineering Department, Faculty of Engineering of the University of Porto (FEUP), Rua Dr. Roberto Frias, 4200-465 Porto, Portugal

Abstract: The main objective of this work is to study the thermal effect induced by the bone cement polymerisation, in the metastatic tumour minimisation and to understand the role of such procedure in bone tumour necrosis. Different numerical simulations were produced for different cement sizes introduced in a cortical and spongy bone tumour, with or without an intramedullary nail in titanium. The numerical models were built according to average dimensions of patients obtained from digital conventional radiographs. The finite element results allow to conclude about the high temperature spread effect in bone material. In conclusion, values greater than 45°C were obtained in models without the intramedullary nail system. High quantities of cement produce thermal necrosis in bone with more pronounced effect in depth. The temperature located on the intramedullary nail induces heat transfer along the axial length of the bone, due to the metallic nail, justified by its high thermal conductivity.

Keywords: bone tumour; bone cement; thermal necrosis; bone metastatic tumour; temperature; numerical model; simulation; nail; titanium; transient analysis.

DOI: 10.1504/IJMEI.2021.111869

International Journal of Medical Engineering and Informatics, 2021 Vol.13 No.1, pp.35 - 43

Received: 31 Oct 2018
Accepted: 06 Mar 2019
Published online: 18 Dec 2020 *

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