Title: Development of new Mg-Zn-Sr alloys for medical purpose

Authors: Michaela Šuliková; Zuzana Molčanová; Beata Ballóková; Juraj Ďurišin; Slávka Martinková; Dagmara Varcholová; Štefan Michalik; Robert Tang-Kong; Logan Ward; Apurva Mehta; Katarína Šuľová; Miloš Fejerčák; Andrea Lachová; Róbert Džunda; Karel Saksl

Addresses: Faculty of Science, Institute of Physics, Pavol Jozef Šafárik University in Košice, Košice 041 80, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia ' Faculty of Electrical Engineering and Informatics, Department of Technologies in Electronics, Technical University of Košice, Letná 9, 042 00 Košice, Slovakia ' Faculty of Science, Institute of Physics, Pavol Jozef Šafárik University in Košice, Košice 041 80, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia; Faculty of Materials Metallurgy and Recycling, Technical University of Košice, Letna 9, 042 00 Košice, Slovakia ' Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, UK ' Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA ' The Computational Science Division, Argonne National Laboratory, 9700 S. Cass Avenue, Lemont, IL 60439, USA ' Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia; Faculty of Materials Metallurgy and Recycling, Technical University of Košice, Letna 9, 042 00 Košice, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia; Faculty of Science, Institute of Physics, Pavol Jozef Šafárik University in Košice, Košice 041 80, Slovakia ' Faculty of Science, Institute of Physics, Pavol Jozef Šafárik University in Košice, Košice 041 80, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia ' Institute of Materials Research, Slovak Academy of Sciences, Watsonova 47, 040 01 Košice, Slovakia; Faculty of Science, Institute of Physics, Pavol Jozef Šafárik University in Košice, Košice 041 80, Slovakia

Abstract: In surgery, in addition to joint replacement, which requires permanent implantation of the prosthesis into the human body, there are many other clinical cases where fixation or mechanical support are only temporarily needed during the healing process of the injured or pathological tissue. In this case, biodegradable materials are the optimal choice as these materials do their job and degrade in the human body thereafter. Amorphous magnesium-zinc based alloys are nowadays a very promising group of metallic glasses (MGs). Unfortunately, the brittleness of Mg-Zn MGs and poor glass forming ability (GFA) have hindered their further application. We have developed a composition series of completely new (not published) ternary Mg-Zn-Sr alloys with attractive properties in terms of possible future applications (density comparable to human bones, wide supercooled liquid region, low rate of degradability, etc.). These ternary alloys will serve as precursors for design of future highly alloyed systems with tuned mechanical properties and dissociation rate in human body.

Keywords: Mg-Zn-Sr; alloys; X-ray diffraction; nanoindentation; degradation rate; thermal stability.

DOI: 10.1504/IJNT.2020.111327

International Journal of Nanotechnology, 2020 Vol.17 No.7/8/9/10, pp.573 - 582

Published online: 20 Nov 2020 *

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