Title: Histopathological cells segmentation using exponential grasshopper optimisation algorithm-based fuzzy clustering method

Authors: Varun Tiwari; S.C. Jain

Addresses: Department of Computer Science and Engineering, Rajasthan Technical University, Kota, India ' Department of Computer Science and Engineering, Rajasthan Technical University, Kota, India

Abstract: Automated cell segmentation in histopathological images is a challenging problem due to the complexities of these images. In this paper, a new exponential grasshopper optimisation algorithm is presented which is further used to find the optimal fuzzy clusters for segmenting the cells in histopathological images. For better cluster quality, compactness is considered as the objective function. The performance of the proposed method is validated in terms of F1 score and aggregated Jaccard index value on two standard histopathological image datasets, namely TNBC patients cancer dataset and UCSB bio segmentation images dataset. The simulation results show the effectiveness of the proposed method over other state-of-the-art clustering segmentation methods such as K-means and fuzzy c-means.

Keywords: histopathological images; cell segmentation; nature-inspired algorithm; grasshopper optimisation algorithm; GOA.

DOI: 10.1504/IJIIDS.2020.109452

International Journal of Intelligent Information and Database Systems, 2020 Vol.13 No.2/3/4, pp.118 - 138

Received: 26 Mar 2019
Accepted: 02 Jul 2019

Published online: 25 Aug 2020 *

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