Title: Silicon on insulator-based microring resonator and Au nanofilm Krestchmann-based surface plasmon resonance glucose sensors for lab-on-a-chip applications

Authors: HarbiSetyo Nugroho; Lilik Hasanah; Chandra Wulandari; RoerEka Pawinanto; Mohamad Hazwan Haron; Ahmad RifqiMd Zain; DillaDuryha Berhanuddin; Budi Mulyanti; Preetpal Singh; P. Susthitha Menon

Addresses: Department of Physics Education, UniversitasPendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia ' Department of Physics Education, UniversitasPendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia ' Department of Physics Education, UniversitasPendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia ' Department of Electrical Engineering Education, UniversitasPendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia ' Institute of Microengineering and Nanoelectronics (IMEN), UniversitiKebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia ' Institute of Microengineering and Nanoelectronics (IMEN), UniversitiKebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia; 213 John McKay Lab, Harvard University, John A. Paulson Building, 31 Oxford St., Cambridge, MA 02138, USA ' Institute of Microengineering and Nanoelectronics (IMEN), UniversitiKebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia ' Department of Electrical Engineering Education, UniversitasPendidikan Indonesia (UPI), Bandung 40154 Jawa Barat, Indonesia ' Centre for Reliability Science and Technologies, Chang Gung University, Taoyuan City 33302, Taiwan ' Institute of Microengineering and Nanoelectronics (IMEN), UniversitiKebangsaan Malaysia (UKM), 43600 Bangi, Selangor, Malaysia

Abstract: Diabetes mellitus is a disease of metabolic disorders where human blood contains a high amount of sugar level for a prolonged period. This study aims to simulate the effectiveness of sensors based on microring resonator (MRR) and surface plasmon resonance (SPR) for diabetes monitoring. The results show that a sensor based on MRR and SPR provides the ability to detect low levels of glucose concentration as low as 7 mM (0.13%) and the ability to detect resonance shift for very small glucose concentration change. Therefore, the sensor based on MRR and SPR can be used for diabetes monitoring. The sensitivity of the sensor based on MRR and SPR is 85.84 nm/RIU and 116.69°/RIU, respectively. These findings are important for the development of diabetes monitoring based on MRR or SPR.

Keywords: surface plasmon resonance; Kretschmann; microring resonator; glucose sensor; silicon-on-insulator; Au nanofilm.

DOI: 10.1504/IJNT.2020.109348

International Journal of Nanotechnology, 2020 Vol.17 No.1, pp.29 - 41

Published online: 03 Sep 2020 *

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