Title: Pragmatic realities on brain imaging techniques and image fusion for Alzheimer's disease

Authors: P.S. Jagadeesh Kumar; Yang Yung; Mingmin Pan

Addresses: Biomedical Engineering Research Centre (BMERC), College of Engineering, Nanyang Technological University, 50 Nanyang Drive, Research Techno Plaza, 637553, Singapore ' Biomedical Engineering Research Centre (BMERC), College of Engineering, Nanyang Technological University, 50 Nanyang Drive, Research Techno Plaza, 637553, Singapore ' Biomedical Engineering Research Centre (BMERC), College of Engineering, Nanyang Technological University, 50 Nanyang Drive, Research Techno Plaza, 637553, Singapore

Abstract: Alzheimer's disease is the absolute generous of age-related neurodegenerative syndrome. It specifies substantial brain atrophy, amnesia and major neuro-logic disintegration. Brain imaging techniques has been progressively employed for medical explanation and variant diagnosis, and to afford understanding into the paraphernalia on functional and structural measurements of the brain, sketches of dimensional distribution besides their normal antiquity and progression over time. This paper makes an exertion in performing a practical virtuosity on brain imaging techniques and image fusion for the diagnosis of Alzheimer's disease. Several brain imaging techniques like computerised tomography, single-photon emission computed tomography, magnetic resonance spectroscopy, positron emission tomography, magnetoencephalo-graphy, magnetic resonance imaging diffusion tensor imaging was evaluated for Alzheimer's disease based on their degree of confidence, quality, volumetry, availability, cost and limitations.

Keywords: Alzheimer's disease; brain imaging techniques; image fusion; performance evaluation; neurodegenerative syndrome.

DOI: 10.1504/IJMEI.2020.105655

International Journal of Medical Engineering and Informatics, 2020 Vol.12 No.1, pp.19 - 51

Received: 06 Nov 2017
Accepted: 13 Apr 2018
Published online: 09 Mar 2020 *

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